Anti-SPDL1 Polyclonal Antibody - FITC
Cat: K006833P - FITC
Summary:
| 【Product name】：Anti-SPDL1 Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：54908 | 【Swiss Prot】：Q96EA4 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human SPDL1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
Verified picture: