Anti-ACMSD Polyclonal Antibody - Cy3
Cat: K006867P - Cy3
Summary:
| 【Product name】：Anti-ACMSD Polyclonal Antibody - Cy3 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：130013 | 【Swiss Prot】：Q8TDX5 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human ACMSD | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
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