下载
Anti-BCAM Polyclonal Antibody - Cy3
Cat: K006978P - Cy3
Summary:
【Product name】:Anti-BCAM Polyclonal Antibody - Cy3 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4059 【Swiss Prot】:P50895
【Species reactivity】:Mouse,Human
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human BCAM
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.?
Verified picture: