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Anti-CENPC Polyclonal Antibody - SAlexa Fluor 405
Cat: K006987P - SAlexa Fluor 405
Summary:
【Product name】:Anti-CENPC Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1060 【Swiss Prot】:Q03188
【Species reactivity】:Human
【Tested applications】:IHC
【Immunogen】:Recombinant protein of human CENPC
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
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