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Anti-CFL1 Polyclonal Antibody - SAlexa Fluor 633
Cat: K006993P - SAlexa Fluor 633
Summary:
【Product name】:Anti-CFL1 Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1072 【Swiss Prot】:P23528
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:WB
【Immunogen】:Recombinant protein of human CFL1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
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