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Anti-TAB3 Polyclonal Antibody - SAlexa Fluor 568
Cat: K007097P - SAlexa Fluor 568
Summary:
【Product name】:Anti-TAB3 Polyclonal Antibody - SAlexa Fluor 568 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:257397 【Swiss Prot】:Q8N5C8
【Species reactivity】:Mouse,Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human TAB3
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.?
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