Anti-PLEKHG6 Polyclonal Antibody - Cy5
Cat: K007110P - Cy5
Summary:
| 【Product name】：Anti-PLEKHG6 Polyclonal Antibody - Cy5 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：55200 | 【Swiss Prot】：Q3KR16 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PLEKHG6 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
Verified picture: