Anti-RAD17 Polyclonal Antibody - SAlexa Fluor 488
Cat: K007157P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-RAD17 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5884 | 【Swiss Prot】：O75943 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RAD17 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage.
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