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Anti-WDR77 Polyclonal Antibody
Cat: K007226P
Summary:
【Product name】:Anti-WDR77 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:79084 【Swiss Prot】:Q9BQA1
【Species reactivity】:Mouse,Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human WDR77
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).
Verified picture:
Western blot analysis with WDR77 antibody diluted at 1:1000; Lane 1-5:K-562,HeLa,293T,Jurkat
Immunohistochemistry of paraffin-embedded Human breast cancer with WDR77 antibody diluted at 1:20