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Anti-WFS1 Polyclonal Antibody - SAlexa Fluor 350
Cat: K007261P - SAlexa Fluor 350
Summary:
【Product name】:Anti-WFS1 Polyclonal Antibody - SAlexa Fluor 350 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:7466 【Swiss Prot】:O76024
【Species reactivity】:Mouse,Human
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human WFS1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.
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