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Anti-FGR Polyclonal Antibody - FITC
Cat: K007297P - FITC
Summary:
【Product name】:Anti-FGR Polyclonal Antibody - FITC 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:2268 【Swiss Prot】:P09769
【Species reactivity】:Human
【Tested applications】:ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human FGR
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.?
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