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Anti-CRMP1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K007402P - SAlexa Fluor 640
Summary:
【Product name】:Anti-CRMP1 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1400 【Swiss Prot】:Q14194
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human CRMP1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Collapsin response mediator protein 1, encoded by the?CRMP1?gene, is a human?protein?of the?CRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.
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