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Anti-PCBD1 Polyclonal Antibody
Cat: K007482P
Summary:
【Product name】:Anti-PCBD1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5092 【Swiss Prot】:P61457
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:WB,IHC
【Immunogen】:Recombinant protein of human PCBD1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with PCBD1 antibody diluted at 1:1000; Lane: Mouse liver,Mouse kidney,Mouse pancreas,Rat liver
Immunohistochemistry of paraffin-embedded Human breast cancer with PCBD1 antibody diluted at 1:40