Anti-CBX3 Polyclonal Antibody - Cy5
Cat: K007513P - Cy5
Summary:
| 【Product name】：Anti-CBX3 Polyclonal Antibody - Cy5 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：11335 | 【Swiss Prot】：Q13185 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CBX3 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.?
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