Anti-MCAM Polyclonal Antibody - HRP
Cat: K007604P - HRP
Summary:
| 【Product name】：Anti-MCAM Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4162 | 【Swiss Prot】：P43121 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human MCAM | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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