Anti-TNFRSF8 Polyclonal Antibody - Biotin
Cat: K007683P - Biotin
Summary:
| 【Product name】：Anti-TNFRSF8 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：943 | 【Swiss Prot】：P28908 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human TNFRSF8 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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