Anti-CASP8AP2 Polyclonal Antibody
Cat: K007707P
Summary:
| 【Product name】：Anti-CASP8AP2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9994 | 【Swiss Prot】：Q9UKL3 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human CASP8AP2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Verified picture:
Western blot analysis with CASP8AP2 antibody diluted at 1:10000; Lane:K-562,293T
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue with CASP8AP2 antibody diluted at 1:20