Anti-CASP8AP2 Polyclonal Antibody - HRP
Cat: K007707P - HRP
Summary:
| 【Product name】：Anti-CASP8AP2 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9994 | 【Swiss Prot】：Q9UKL3 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CASP8AP2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
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