Anti-HRG Polyclonal Antibody
Cat: K007728P
Summary:
| 【Product name】：Anti-HRG Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3273 | 【Swiss Prot】：P04196 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human HRG | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with HRG antibody diluted at 1:50