Anti-IGF2R Polyclonal Antibody - SAlexa Fluor 532
Cat: K007738P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-IGF2R Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3482 | 【Swiss Prot】：P11717 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human IGF2R | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
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