Anti-KDM4C Polyclonal Antibody - SAlexa Fluor 350
Cat: K007745P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-KDM4C Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：23081 | 【Swiss Prot】：Q9H3R0 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human KDM4C | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
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