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Anti-KCNMB4 Polyclonal Antibody
Cat: K007751P
Summary:
【Product name】:Anti-KCNMB4 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:27345 【Swiss Prot】:Q86W47
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human KCNMB4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.
Verified picture:
Western blot analysis with KCNMB4 antibody diluted at 1:1000;Lane: Mouse brain
Immunohistochemistry of paraffin-embedded Human liver cancer with KCNMB4 antibody diluted at 1:30