Anti-ATP2A1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K007768P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-ATP2A1 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：487 | 【Swiss Prot】：O14983 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human ATP2A1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.?
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