Anti-NPR2 Polyclonal Antibody
Cat: K007778P
Summary:
| 【Product name】：Anti-NPR2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4882 | 【Swiss Prot】：P20594 |
| 【Species reactivity】：Mouse,Rat,Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human NPR2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity.?
Verified picture:
Western blot analysis with NPR2 antibody diluted at 1:1000;Lane: Mouse liver
Immunohistochemistry of paraffin-embedded Human ovarian cancer with NPR2 antibody diluted at 1:50