Anti-PMS2 Polyclonal Antibody - SAlexa Fluor 350
Cat: K007796P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-PMS2 Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5395 | 【Swiss Prot】：P54278 |
| 【Species reactivity】：Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human PMS2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
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