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Anti-PMS2 Polyclonal Antibody - SAlexa Fluor 750
Cat: K007796P - SAlexa Fluor 750
Summary:
【Product name】:Anti-PMS2 Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5395 【Swiss Prot】:P54278
【Species reactivity】:Human
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human PMS2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
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