Anti-RCC1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K007807P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-RCC1 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1104 | 【Swiss Prot】：P18754 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of human RCC1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
RCC1 (regulator of chromosome condensation 1), increases the rate at which Ran exchanges GDP for GTP. Ran GAP1 opposes the effects of RCC1 by increasing the rate at which Ran hydrolyzes GTP to GDP. A protein designated Ran BP1 has no intrinsic GAP activity and functions as a GEF inhibitor, deactivating RCC1 and thereby indirectly increasing the ratio of Ran GDP to Ran GTP. Ran BP2 has been proposed as the Ran GTP docking site at the periphery of the nuclear pore complex.
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