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Anti-SIGLEC8 Polyclonal Antibody - SAlexa Fluor 750
Cat: K007829P - SAlexa Fluor 750
Summary:
【Product name】:Anti-SIGLEC8 Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:27181 【Swiss Prot】:Q9NYZ4
【Species reactivity】:Human
【Tested applications】:WB
【Immunogen】:A synthetic peptide of human SIGLEC8
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM, and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein.
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