Anti-SIGLEC8 Polyclonal Antibody - Cy5.5
Cat: K007829P - Cy5.5
Summary:
| 【Product name】：Anti-SIGLEC8 Polyclonal Antibody - Cy5.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：27181 | 【Swiss Prot】：Q9NYZ4 |
| 【Species reactivity】：Human | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human SIGLEC8 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM, and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein.
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