Anti-SLC17A1 Polyclonal Antibody - SAlexa Fluor 750
Cat: K007845P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-SLC17A1 Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6568 | 【Swiss Prot】：Q14916 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of human SLC17A1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1? and HNF-3∫. Indomethacin and salicylate inhibit NPT1-mediated PAH transport.
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