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Anti-TBX1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K007865P - SAlexa Fluor 640
Summary:
【Product name】:Anti-TBX1 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:6899 【Swiss Prot】:O43435
【Species reactivity】:Human
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of human TBX1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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