Anti-XPC Polyclonal Antibody - SAlexa Fluor 532
Cat: K007896P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-XPC Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7508 | 【Swiss Prot】：Q01831 |
| 【Species reactivity】：Rat,Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human XPC | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
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