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Anti-HNF1A Polyclonal Antibody - SAlexa Fluor 640
Cat: K007901P - SAlexa Fluor 640
Summary:
【Product name】:Anti-HNF1A Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:6927 【Swiss Prot】:P20823
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human HNF1A
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
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