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Anti-NANOS1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K007934P - SAlexa Fluor 488
Summary:
【Product name】:Anti-NANOS1 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:340719 【Swiss Prot】:Q8WY41
【Species reactivity】:Human,Mouse
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human NANOS1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Nanos1, also known as NOS1, is a 292 amino acid protein that localizes to the perinuclear region of the cytoplasm and contains one nanos-type zinc finger. Expressed at high levels in spermatogonia and present at lower levels in fetal ovaries, Nanos1 forms a complex with Pumilio 2 and functions to regulate the translation of select mRNAs, specifically via association with the 3’-UTR of its mRNA targets. Additionally, Nanos1 is required for the establishment and maintenance of germline stem cells, as it prevents their premature entry into oogenesis.
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