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Anti-SULF2 Polyclonal Antibody - SAlexa Fluor 555
Cat: K007949P - SAlexa Fluor 555
Summary:
【Product name】:Anti-SULF2 Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:55959 【Swiss Prot】:Q8IWU5
【Species reactivity】:Human,Mouse
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human SULF2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
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