Anti-MSH2 Polyclonal Antibody
Cat: K007959P
Summary:
| 【Product name】：Anti-MSH2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4436 | 【Swiss Prot】：P43246 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：ELISA,WB,IHC | |
| 【Immunogen】：A synthetic peptide of human MSH2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with MSH2 antibody diluted at 1:500; Lane: HepG2,293T,SKOV3,HeLa,Mouse testis,Rat testis
Immunohistochemistry of paraffin-embedded Human colorectal cancer with MSH2 antibody at dilution 1:20.