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Anti-WHSC1 Polyclonal Antibody - RBITC
Cat: K007976P - RBITC
Summary:
【Product name】:Anti-WHSC1 Polyclonal Antibody - RBITC 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:7468 【Swiss Prot】:O96028
【Species reactivity】:Human
【Tested applications】:WB ELISA IHC ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human WHSC1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
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