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Anti-DNAJC2 Polyclonal Antibody
Cat: K008007P
Summary:
【Product name】:Anti-DNAJC2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:27000 【Swiss Prot】:Q99543
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of human DNAJC2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.?
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with DNAJC2 antibody diluted at 1:50