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Anti-DR1 Polyclonal Antibody
Cat: K008024P
Summary:
【Product name】:Anti-DR1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1810 【Swiss Prot】:Q01658
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human DR1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.?
Verified picture:
Western blot analysis with DR1 antibody diluted at 1:1000;Lane: Jurkat,NIH3T3
Immunohistochemistry of paraffin-embedded Human ovarian cancer with DR1 antibody diluted at 1:25