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Anti-GNB1L Polyclonal Antibody
Cat: K008026P
Summary:
【Product name】:Anti-GNB1L Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:54584 【Swiss Prot】:Q9BYB4
【Species reactivity】:Human,Mouse
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human GNB1L
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene.
Verified picture:
Western blot analysis with GNB1L antibody diluted at 1:1000;Lane: Jurkat,A549
Immunohistochemistry of paraffin-embedded Human liver cancer with GNB1L antibody diluted at 1:50