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Anti-IL17A Polyclonal Antibody
Cat: K008040P
Summary:
【Product name】:Anti-IL17A Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3605 【Swiss Prot】:Q16552
【Species reactivity】:Human
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human IL17A
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Verified picture:
Western blot analysis with IL17A antibody diluted at 1:1000;Lane: Mouse thymus
Immunohistochemistry of paraffin-embedded Human colorectal cancer with IL17A antibody diluted at 1:30