Anti-MECOM Polyclonal Antibody
Cat: K008042P
Summary:
| 【Product name】：Anti-MECOM Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2122 | 【Swiss Prot】：Q03112 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human MECOM | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Verified picture:
Western blot analysis with MECOM antibody diluted at 1:500;Lane: Mouse heart.
Immunohistochemistry of paraffin-embedded Human ovarian cancer with MECOM antibody diluted at 1:30