Anti-TONSL Polyclonal Antibody
Cat: K008085P
Summary:
| 【Product name】：Anti-TONSL Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4796 | 【Swiss Prot】：Q96HA7 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：ELISA,IHC,WB | |
| 【Immunogen】：Recombinant protein of human TONSL | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
Verified picture:
Western blot analysis with TONSL antibody diluted at 1:400;Lane:Mouse brain
Immunohistochemistry of paraffin-embedded Human prostate cancer using TONSL antibody diluted at 1:50