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Anti-CBX8 Polyclonal Antibody
Cat: K008123P
Summary:
【Product name】:Anti-CBX8 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:57332 【Swiss Prot】:Q9HC52
【Species reactivity】:Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human CBX8
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Verified picture:
Western blot analysis with CBX8 antibody diluted at 1:1000; Lane: MCF7
Immunohistochemistry of paraffin-embedded Human endometrial cancer with CBX8 antibody diluted at 1:35