Anti-EMC8 Polyclonal Antibody
Cat: K008130P
Summary:
| 【Product name】：Anti-EMC8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：10328 | 【Swiss Prot】：O43402 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human EMC8 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Verified picture:
Western blot analysis with EMC8 antibody diluted at 1:1000; Lane:A549,293T
Immunohistochemistry of paraffin-embedded Human cervical cancer with EMC8 antibody diluted at 1:30