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Anti-PRPF8 Polyclonal Antibody
Cat: K008159P
Summary:
【Product name】:Anti-PRPF8 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:10594 【Swiss Prot】:Q6P2Q9
【Species reactivity】:Human,Mouse
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human PRPF8
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Verified picture:
Western blot analysis with PRPF8 antibody diluted at 1:1000; Lane:293T,K-562,Raji,Hela,NIH3T3,Jurkat,A431
Immunohistochemistry of paraffin-embedded Human esophageal cancer with PRPF8 antibody diluted at 1:50