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Anti-BAIAP2 Polyclonal Antibody - Biotin
Cat: K008178P - Biotin
Summary:
【Product name】:Anti-BAIAP2 Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:10458 【Swiss Prot】:Q9UQB8
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human BAIAP2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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