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Anti-KIF3A Polyclonal Antibody - Cy5
Cat: K008179P - Cy5
Summary:
【Product name】:Anti-KIF3A Polyclonal Antibody - Cy5 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:11127 【Swiss Prot】:Q9Y496
【Species reactivity】:Human,Mouse
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human KIF3A
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Kinesin-like protein KIF3A?is a?protein?that in humans is encoded by the?KIF3A?gene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.
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