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Anti-CHRNA4 Polyclonal Antibody - SAlexa Fluor 647
Cat: K008197P - SAlexa Fluor 647
Summary:
【Product name】:Anti-CHRNA4 Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1137 【Swiss Prot】:P43681
【Species reactivity】:Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human CHRNA4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.?
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