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Anti-PADI4 Polyclonal Antibody - SAlexa Fluor 647
Cat: K008211P - SAlexa Fluor 647
Summary:
【Product name】:Anti-PADI4 Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:23569 【Swiss Prot】:Q9UM07
【Species reactivity】:Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human PADI4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O protein L-citrulline + NH3.
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